Automated high-throughput registration for localizing 3D mouse brain gene expression using ITK
Please use this identifier to cite or link to this publication: http://hdl.handle.net/1926/15
New: Prefer using the following doi: https://doi.org/10.54294/9nkczd
The Allen Brain Atlas (ABA) project aims to create a cellular-resolution, genome-wide map of gene expression in the adult mouse brain. The resulting in situ hybridization (ISH) image data will be available free-of-charge to the public. Additionally, we are developing an informatics pipeline to support searching of the data by anatomic region and expression level and/or pattern. This paper describes a robust, high-throughput registration scheme to automatically annotate hierarchical brain structures in the ISH imagery.