The Insight Journal is an Open Access on-line publication covering the domain of medical image processing and visualization.

The unique characteristics of the Insight Journal include:

- Open-access to articles, data, code, and reviews
- Open peer-review that invites discussion between reviewers and authors
- Emphasis on reproducible science via automated code compilation and testing
- Support for continuous revision of articles, code, and reviews


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Real-Time Ultrasound Image Analysis for the Insight Toolkit
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We have successfully created a software environment in which ultrasound data can be manipulated by, ITK (the Insight Tool-Kit), in real-time. We were able to access each frame generated within the resident computer of a TerasonTM Ultrasound Machine, convert [...]

Open Topology: A Toolkit for Brain Isosurface Correction
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Isosurface extraction from brain images often creates handles between brain folds that are anatomically separated. Although manual editing could optimally correct these anatomical errors, it is not realistic due the size of the 3D data and the convoluted [...]

Comparison of Salient Point Detection Methods for 3D Medical Images
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Salient points are used for various applications, such as medical image registration, tracking, stereoscopic matching. The purpose of this paper is to compare two commonly used methods to extract salient points in 3D medical images. We give an interpretation [...]

A DICOM-based Software Infrastructure for Data Archiving
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In this paper , we propose an extension to the National Library of Medicine's Insight Segmentation and Registration Toolkit (ITK. www.itk.org) with a companion image access and archival system that merges the image transfer capabilities of DICOM with DSpace [...]

Creation and Demonstration of a Framework for Handling Paths in ITK
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A hierarchy of path data types and basic path filters were added to ITK, providing a general framework for curves that map a scalar value to a point in n-dimensional space. The framework supports curves that are either continuous (parametric curves) or [...]

ITK-based Registration of Large Images from Light Microscopy: A Biomedical Application
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Inactivation of the retinoblastoma gene in mouse embryos results in morphological changes in the placenta, which has been shown to affect fetal survivability. The construction of a 3D virtual placenta aids in accurately quantifying structural changes [...]

N-Dimensional Path Optimization:  The Implementation of a Novel Algorithm in ITK
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Using the path framework we previously added to ITK, we implemented a novel algorithm for n-dimensional path optimization, which we call the ND Swath (NDS). NDS uses dynamic programming to globally optimize the placement of a path within an image, subject to [...]

Unsupervised Segmentation for Myofiber Counting in Immunofluorescent Microscopy Images
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The gold standard for measuring muscle regeneration in muscular dystrophy therapies is counting the number of dystrophin-positive muscle fibers on a cryostat muscle section immunostained for dystrophin. The standard process of manually counting a few thousand [...]

Impact of motion correction on the quantitative analysis of DCE-MR Images
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Dynamic magnetic resonance imaging (DCE-MRI) carried out with contrast media such as Gd-chelate complex (Gd-DTPA) allows the non-invasive assessment of microcirculatory characteristics of malignant lesions. Quantitative estimation of lesion [...]

BioImage Suite: An integrated medical image analysis suite
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BioImage Suite is an integrated image analysis software suite developed at Yale. It uses a combination of C++ and Tcl in the same fashion as that pioneered by the Visualization Toolkit (VTK) and it leverages both VTK and the Insight Toolkit. It has [...]

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Most Recent Reviews
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Worked very well and was easy to build
A Skull-Stripping Filter for ITK
by Jared Becksfort on 2017-09-19 16:03:36
Very interesting work
Isotropic and Steerable Wavelets in N...
by Le Zheng on 2017-06-02 11:07:04
Valuable contribution
A new implementation of...
by Dženan Zukić on 2016-07-28 15:40:50
Simple interface
A Skull-Stripping Filter for ITK
by Todd Jensen on 2016-05-30 08:00:15
A useful function, but with some build...
Walk In A Triangulation : Straight Walk
by Davis Vigneault on 2015-06-09 09:57:49
A meaningful contribution with...
Exact Geometrical Predicate: Point in...
by Davis Vigneault on 2015-06-09 11:10:14
Useful tool for kinetic analysis of PET...
InsightToolkit Kinetic Analysis...
by Matthew Mccormick on 2014-11-21 18:34:13
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ISSN 2327-770X
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