Local Shape Analysis using MANCOVA
Gross shape measures such as volume have been widely used in statistical analysis of anatomical structures. Statistical shape analysis methods have emerged within the last decade to allow for a localized analysis of shape. Most shape analysis frameworks are [...]

Implementing the Automatic Generation of 3D Statistical Shape Models with ITK
Statistical Shape Models are a popular method for segmenting three-dimensional medical images. To obtain the required landmark correspondences, various automatic approaches have been proposed. In this work, we present an improved version of minimizing the [...]

Framework for the Statistical Shape Analysis of Brain Structures using SPHARM-PDM
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Shape analysis has become of increasing interest to the neuroimaging community due to its potential to precisely locate morphological changes between healthy and pathological structures. This manuscript presents a comprehensive set of tools for the [...]

Biomarker Detection in Whole Slide Imaging based on Statistical Color Models
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This paper presents a technique for immunostaining biomarker detection in digital slides. We treat immunostaining detection as a color image analysis problem and build statistical color models using a large number of labeled positive and negative [...]

Assessment of Peri-Articular Implant Fitting Based on Statistical Finite Element Modeling
We present a framework for statistical finite element analysis allowing performing statistical statements of biomechanical performance of peri-articular implants across a given population. In this paper, we focus on the design of orthopaedic implants that fit [...]

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