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ITK currently comes with a 2D binary thinning (skeletonisation) method, but does not support 3D or higher. This paper documents a new itkBinaryThinningImageFilter3D and recommends to rename the current filter as itkBinaryThinningImageFilter2D.
The 3D [...]

In this document it is described the implementation of the flux driven automatic centerline extraction
algorithm proposed by Bouix et al. in 2004. This is based on a skeletonisation algorithm initially
proposed by Siddiqi et al. in 2002, using properties of [...]
